Science-Based Education · 74 Protocols
The friendliest
place to learn
peptide science
Everyone is talking about peptides. Very few people actually understand them.
Peptide Academy changes that — with clear, cited, welcoming education for curious minds and serious practitioners alike.
74
Protocol Guides
600+
Research Citations
3
Learning Tracks
$25
Starts From
Featured Protocols
Recovery
Research
BPC-157
Body Protection Compound
Accelerates tendon, ligament, and gut repair via angiogenesis and growth factor upregulation.
TendonGutNeuro
Weight Loss
FDA Approved
Semaglutide
GLP-1 Receptor Agonist
Longevity
Research
NAD+
Nicotinamide Adenine Dinucleotide
+ 71 more protocols →
Peer-reviewed citations on every guide
FDA regulatory status clearly labeled
No ads, no affiliate links, no bias
Updated Aug 2026
Educational use only — not medical advice
Why Peptide Academy
You deserve better than a blog post
Peptides are one of the most searched health topics of 2026 — and also one of the most misunderstood. Reddit threads with bad advice. Influencer content pushing products. Clinical papers no one can read. We built the resource that should have existed years ago.
Every claim is cited
PubMed links on every mechanism and dosing claim. No opinions dressed as facts.
Designed for real humans
Beginner-friendly language without sacrificing scientific accuracy. Learn at your own pace.
Complete, not curated
74 full protocol guides — not 10 popular ones. If it exists and matters, it's here.
Honest about the unknowns
When human data is limited, we say so. When evidence is preclinical only, we say so.
Most Popular
GLP-1 & Weight Loss Peptides
Semaglutide, tirzepatide, cagrilintide — the science behind the shots everyone is asking about. What the trials actually showed.
Most Searched
Recovery & Healing
BPC-157, TB-500, the Wolverine Stack — every mechanism and protocol for athletes and anyone healing from injury.
Fast Growing
Longevity & Anti-Aging
NAD+, SS-31, FOXO4-DRI, Epitalon — the frontier science of extending healthspan at the cellular level.
Learning Paths
Pick your track
Whether you've never heard of a peptide or you're a practitioner building protocols, there's a path designed for where you are right now.
🌱 Beginner
Peptide Foundations
Start here. Learn what peptides are, how they work, why they're different from supplements, and how to think about them safely.
What is a peptide? (vs. protein, vs. drug)
How peptides enter your body
FDA status — what it actually means
Reading a protocol document
Reconstitution 101
Start Learning
📖 Intermediate
Protocol Builder
Deep-dive into individual protocols. Understand mechanisms, dosing, stacking rationale, contraindications, and how to build goal-specific programs.
Recovery: Wolverine Stack mechanics
GH optimization: GHRH + GHRP synergy
GLP-1 class: comparing all options
Cognitive stacks: Semax + Selank
Stacking principles & timing
Explore Protocols
🔬 Advanced
Frontier Science
For practitioners and advanced researchers. Mitochondrial peptides, senolytics, triple GLP-1 agonists, IGF-1 LR3, follistatin, and cutting-edge longevity science.
Mitokines: SS-31, MOTS-C, Humanin
Senolytic therapy: FOXO4-DRI
Triple agonist weight loss (Retatrutide)
Advanced GH axis optimization
Bioregulator peptides (Khavinson)
Go Deep
Protocol Library
74 protocol guides
Mechanism · Dosing · Reconstitution · Stacking · Contraindications · References
Dosing Calculator
Reconstitution made simple
Pick a peptide, enter your weight and vial — get your exact draw volume, syringe units, and timing notes. Updates live as you adjust.
⚗️ Reconstitution Setup
Vial Size
Bacteriostatic Water
⏱ Timing: Load a peptide to see timing guidance.
💉 Your Draw
50
units on a U-100 syringe
Syringe fill level
0
25
50
75
100u
Dose
500mcg
Draw volume
0.50mL
Frequency
1× daily
Vial lasts
4days
Educational only · Not medical advice · Consult your provider
Stack Protocols
Peptides work better together
These are the most studied multi-peptide combinations — each one targeting a specific outcome with synergistic mechanisms explained.
Wolverine Recovery
The gold standard healing combination
BPC-157 drives local angiogenesis and gut healing. TB-500 mobilizes systemic stem cells and reduces inflammation. Together they cover every phase of tissue repair.
BPC-157TB-500
GLOW Aesthetic
Inside-out skin, hair, and tissue repair
Triple mechanism: angiogenesis (BPC-157) + cell migration (TB4) + collagen synthesis (GHK-cu). Most popular post-procedure aesthetic protocol.
BPC-157TB4GHK-cu
GH Optimization
3–10× amplified GH pulse
GHRH (CJC-1295) + GHRP (Ipamorelin) — two complementary mechanisms producing a synergistic GH pulse. The foundational anti-aging GH secretagogue protocol.
CJC-1295Ipamorelin
Metabolic Reset
Three fat-loss mechanisms in one
GLP-1 agonist for appetite suppression, AOD-9604 for direct lipolysis, MOTS-C for AMPK activation and fat browning. Three independent metabolic pathways.
GLP-1 RAAOD-9604MOTS-C
Nootropic Clarity
Sharp focus without the edge
Semax drives BDNF and dopaminergic focus. Selank provides GABA-mediated calm without sedation. NAD+ powers neurons. Balanced cognitive enhancement.
SemaxSelankNAD+
Longevity Protocol
Cellular rejuvenation from three angles
NAD+ replenishes coenzyme pools for sirtuin activation. SS-31 restores mitochondrial cristae. FOXO4-DRI selectively clears senescent cells.
NAD+SS-31FOXO4-DRI
Side-by-Side
Weight loss peptide comparison
How the major GLP-1 class compounds compare by evidence level, mechanism, and clinical outcomes.
| Compound | Mechanism | Mean Weight Loss | Half-Life | FDA Status | Once Weekly |
|---|---|---|---|---|---|
| Semaglutide GLP-1 Receptor Agonist | GLP-1 RA | ~15–17% | ~7 days | FDA Approved | ✓ |
| Tirzepatide GLP-1 + GIP Dual Agonist | GLP-1+GIP RA | ~22.5% | ~5 days | FDA Approved | ✓ |
| Retatrutide Triple Agonist (GLP-1+GIP+Glucagon) | GLP-1+GIP+Glucagon | ~24.2% | ~6 days | Phase III | ✓ |
| AOD-9604 hGH Fragment 176-191 | Direct lipolysis | Targeted fat | ~30 min | Research | — |
| Cagrilintide Amylin Analogue | Amylin/Satiety | Additive (combo) | ~7–8 days | Phase III | ✓ |
Science Made Simple
Explained like you're twelve
Complex peptide science translated into everyday analogies. Tap any card to reveal the real science underneath.
📱
What is a peptide?
Your Body's Text Messages
"Peptides are like DMs your body sends between cells. Hormones are the long emails. Peptides are the quick texts — short, specific, and gone in minutes."
Peptides are chains of 2–50 amino acids linked by peptide bonds. Unlike large protein hormones, their small size allows rapid receptor binding and clearance. Synthetic peptides mimic endogenous signaling molecules — they speak the body's native biochemical language, binding specific receptors to trigger targeted downstream effects with minimal off-target activity.
Beginner
🔑
Receptor Selectivity
The Lock and Key
"Every peptide has a shape. Every receptor is a lock. Ipamorelin only fits the GH lock — it can't accidentally open the cortisol door. That's why it has almost no side effects."
Peptide-receptor specificity is determined by tertiary structure. Ipamorelin's selectivity for GHS-R1a (ghrelin receptor) without activating ACTH or cortisol pathways distinguishes it from earlier GHRPs. This selectivity arises from its unique pentapeptide structure — Aib-His-D-2-Nal-D-Phe-Lys-NH₂ — which achieves high GH release with a markedly cleaner side-effect profile.
Beginner
🏗️
BPC-157 Mechanism
The Construction Foreman
"BPC-157 is the foreman on an injury site. It calls in three crews: plumbers (new blood vessels), electricians (nerve repair), and framers (tendon/collagen). TB-500 is the general contractor who shows up anywhere on the job site regardless of where you inject it."
BPC-157 promotes angiogenesis via VEGF upregulation and activates the FAK-paxillin pathway for accelerated cell migration. It modulates the NO system for gastroprotection and upregulates GH receptors in fibroblasts. TB-500 (Thymosin Beta-4) promotes systemic actin polymerization via its LKKTETQ domain, driving cell migration and stem cell mobilization regardless of injection site.
Recovery
🏭
GH Peptides vs HGH
The Factory Shift
"Your pituitary is a factory running a GH shift every 90 minutes. Sermorelin rings the shift bell on time. Ipamorelin turns the volume up on each shift. MK-677 keeps the factory running around the clock. Exogenous HGH? That's importing finished product and bypassing the factory — which is why the feedback loop breaks."
GHRH analogs (Sermorelin, Tesamorelin, CJC-1295) stimulate pulsatile GH synthesis at the pituitary. GHRPs (Ipamorelin, GHRP-2) amplify GH pulse amplitude via ghrelin receptor agonism. Combined, they produce 3–10× amplification. Exogenous HGH suppresses endogenous GH via IGF-1 negative feedback on GHRH neurons and somatostatin upregulation — permanently altering axis sensitivity with prolonged use.
Growth Hormone
📝
GLP-1 / Semaglutide
The Laminated Note
"Your gut sends a 'we're full' note to your brain after eating. Normally that note disappears in 2 minutes. Semaglutide is the same note written on laminated paper — it lasts 7 days. Same message, same receptor, brain just can't forget it."
Native GLP-1 has a half-life of ~2 minutes due to DPP-4 cleavage. Semaglutide achieves ~7-day half-life through C18 fatty diacid conjugation enabling reversible albumin binding, plus two backbone modifications that confer DPP-4 resistance. It activates GLP-1R in the hypothalamic arcuate nucleus for appetite suppression and in pancreatic β-cells for glucose-dependent insulin secretion.
Weight Loss
🥛
Reconstitution & Storage
The Opened Milk Rule
"Dry peptide powder is like powdered milk — shelf stable for months. Add bacteriostatic water and the clock starts, just like opening a carton of milk. 28 days in the fridge. After that, it's off. Label your vials like you'd date a leftover."
Lyophilized peptides are stable at room temperature for months (some years) due to removal of water that drives hydrolysis and oxidation. Reconstitution in bacteriostatic water (0.9% benzyl alcohol) provides antimicrobial preservation for multi-dose vials. Refrigeration at 2–8°C slows enzymatic degradation. Most peptides maintain ≥95% potency for 28–30 days reconstituted. Freeze-thaw cycles denature structure — never refreeze reconstituted peptides.
Beginner
Peptide Academy
Peptide Science Fundamentals
The most structured, science-backed peptide education available online. 4 weeks. 20 lessons. 4 quizzes. One certificate.
4
Weeks
20
Lessons
70
Quiz Questions
1
Certificate
Week 1 · 5 Lessons
The Foundations
What peptides are and how to use them safely
- 1What is a peptide?
- 2How peptides enter your body
- 3FDA status — what it actually means
- 4Reading a protocol document
- 5Reconstitution & storage
Quiz · 10 Questions
Week 2 · 5 Lessons
The Core Protocols
BPC-157, GH peptides, GLP-1, TB-500, NAD+
- 1BPC-157 — The Repair Peptide
- 2Growth Hormone Peptides
- 3GLP-1 Receptor Agonists
- 4TB-500 & Systemic Healing
- 5NAD+ and Cellular Longevity
Quiz · 10 Questions
Week 3 · 5 Lessons
Stacking & Safety
Building protocols that work — and knowing the limits
- 1The Recovery Stack
- 2The GH Optimization Stack
- 3Weight Loss & Metabolic Stacks
- 4Contraindications & Safety
- 5Tracking Your Protocol
Quiz · 10 Questions
Week 4 · 5 Lessons
Advanced Topics & Your Protocol
Frontier science, sourcing, and your personal plan
- 1Frontier Science: Senolytics & Mitokines
- 2Sourcing & Quality Verification
- 3Working with Practitioners
- 4Building Your Personal Protocol
- 5What Comes Next
Final Exam · 20 Questions
What you'll learn
✓ How peptides work at the molecular level
✓ Safe reconstitution and injection technique
✓ BPC-157, GH peptides, GLP-1, TB-500, NAD+
✓ How to build and stack protocols by goal
✓ Contraindications and safety frameworks
✓ How to source, verify, and track quality